In the course of aquaculture, drugs are broadly used in aquafeed because of the notable effects.However, because of drugs' residue、accumulation、movement and transformation in environment, the mass use of the drugs has brought a series of problems to ecological environment.This paper summarizes the different kinds of drugs' application in the aquafeed at present, as well as the ecological effects caused by the use of the drugs.This paper focuses on the following several respects: drug metabolism in the body of breed animals, fate of drugs in environment, the effects of drugs on aquatic organisms, drugs resistance of bacterium and final impacts on people.It clarified that the application of drugs in aquafeed has close relationship with the ecological environment and human's health, so research of its effects has important theoretical and practical significance.
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