Inhibitory effects of Xanthium serum on BEL-7402 strain cells proliferation
WEI Ai-qin1, LI Xing-wen1, LIAN Xiu-zhen2, YU Fa-Rong2
1. Department of Abdominal Surgery, Tumor Hospital of Gansu Province Lanzhou 730020, China; 2. Experimental Center of Gansu Political Science and Law Institute, Lanzhou 730070, China
he proliferous effects of Xanthium serum on BEL-7402 strain cells were determined with methods of clone formation,and the apoptosis rate of cell was detected with flow cytometer.The results showed that the clones in three Xanthium serum groups(low, medium and high doses) and the 5-FU group were decreased compared to the control group,with the inhibition rates of 18.30%,49.34%, 68.12% and 53.27%,as well as apoptosis rates of 6.1%,8.2%,16.3% and 11.3%,respectively.Xanthium serum has significant toxic and inhibitory effects on BEL-7402 strain cells proliferation.