125I和65Zn在大蟾蜍体内的吸收与分布

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摘要

利用同位素示踪法研究了不同引入途径的¹²⁵I和⁶⁵Zn在大蟾蜍体内的吸收与分布。无论采用注射还是灌喂的方法,蟾蜍对¹²⁵I的残留动态差别不大,都可分为快清除期和平台期,0～2d为快清除期,3～7d为平台期,经过了快清除期之后,残留的¹²⁵I约为起始量的8%,并维持到实验结束。注射了⁶⁵Zn后,0～7d的吸收动态曲线有所起伏,但波动很小,其波动范围为102.4%～114.48%。表明大部分的⁶⁵Zn仍留在体内,几乎没有排出体外。注射⁶⁵Zn的转移并不明显。但灌喂⁶⁵Zn的动态变化则大些,而且转移明显。其活度曲线出现阶段性下降,有两个下降期,第一个下降期为4h～3d,第二个下降期为5～7d。说明灌喂组对⁶⁵Zn的转移比注射组的活跃,但在实验的第7d残留率仍在60%以上。

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关键词 ：大蟾蜍, 125I, 65Zn, 吸收, 分布

Abstract：

The uptake and distribution of ¹²⁵I and ⁶⁵Zn in toad Bufo bufo by different ways were studied.Results showed that the retention dynamics of ¹²⁵I in toad,whether injection or oral administration,had little differences.Both of them composed of a quick elimination stage and followed by a platform stage.During the quick elimination stage(0-2d),the radioactivity decreased significantly.Then the retention rate of ¹²⁵I in toad was maintained about 8% during the following experiment.After injected with ⁶⁵Zn,the retention rate was between 102.4%-114.48%,implying that almost all of ⁶⁵Zn remained in the body,the loss of Zn was not significantly.However,by oral administration,the retention dynamics of ⁶⁵Zn was significantly different from the injection group.The retention rate decreased slowly during the experiment.

Key words： Toad Bufo bufo 125I 65Zn Uptake Distribution

收稿日期: 2006-02-25

Q95-334

基金资助:农业部渔业生态环境重点开放实验室开放基金2003-6

引用本文:

谢瑞文1, 赖亦姬2, 黄瑞兰2, 曹玲2, 王英永2, 钟创光2. 125I和65Zn在大蟾蜍体内的吸收与分布[J]. , 2006, 25(1): 56-58.
XIE Rui-wen1, LAI Yi-ji2, HUANG Rui-lan2, CAO Ling2, WANG Ying-yong2, ZHONG Chuang-guang2. Uptake and Distribution of 125I and 65Zn in Toad Bufo bufo. , 2006, 25(1): 56-58.

链接本文:

http://www.ecolsci.com/CN/Y2006/V25/I1/56

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