In order to study the sanitary quality of farmed oyster from Shenzhen seaboard,the contents of pollutants within it were detected from Jan.2002 to Feb. 2004. The results showed that the concentrations of pollutants were benzene hexachloride(BHC) ND(Could not be detected)～0.100 mg· Kg^-1 wet weight,DDT0.004～0.255 mg·Kg^-1 wet weight,the total bacteria ND～9.3×10⁴ Ind·g^-1,coliforms bacteria ND～5.6×10⁴ Ind(100g)^-1,and PSP ND～34μg·(100g)^-1, and only the Vibrio parahaemolyticus of Crassostrea rivularis from Shajing and Houhai could be detected out.Comparing with the safety standard of non-social effects of pollution on aquatic product(GB18406.4-2001),we found that BHC,DDT,the total bacteria and PSP satisfied the criterion,while the Vibrio parahaemolyticus of Crassostrea rivularis from Shajing and Houhai exceeded and all sites had samples that were beyond the standard of coliforms bacteria.Combined with the contents of heavy metals,we found that the oyster of Shenzhen seaboard was generally polluted by different matters and the sanitary quality was not good.The sanitary quality of Crassostrea rivularis from Zhujiang Mouth and Shenzhen Bay was worse than that of Crassostrea gigas and Crassostrea plicatula from Daya Bay and Dapeng Bay.