镉在大鼠前列腺组织内的蓄积

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Abstract

To investigate the change of cadmium accumulation in prostate glands of normal and castrated rats,sixty healthy male adult SD rats were randomly divided into six groups:control group,castration group,low dose cadmium group(2.5 mμmol•Kg^-1),high dose cadmium group(20 mμmol•Kg^-1),castration and low dose cadmium group(2.5 mμmol•Kg^-1),and castration and high dose cadmium group(20 mμmol•Kg^-1).The prostates of rats were sampled after 18 months of experiment.The cadmium content was measured by using atomic absorption spectrophotometry(AAS).The results showed that cadmium content in castration groups was significantly decreased than in non-castration groups.It was increased after peritoneal injection,but there was not statistical significance in different cadmium dosage groups.Our results showed that cadmium content was increased by long-term cadmium exposure;while it was not increased in castrated rats after long-term cadmium exposure.The underlying mechanism is not clear.

Key words： cadmium castration prostate rat

Received: 25 April 2011

:	R994.6
	Q579.1+1

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	Articles by authors
	LI Jian
	ZHOU Ren-jiang
	LI Qing-chun
	WANG Jing
	GUO Lei-lei
	LUO Zi-guo

Cite this article:

LI Jian,ZHOU Ren-jiang,LI Qing-chun, et al. Accumulation of cadmium in prostate glands of rats[J]. , 2011, 30(2): 170-173.

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http://www.ecolsci.com/EN/ OR http://www.ecolsci.com/EN/Y2011/V30/I2/170

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