Effects of any two dements of S(Na₂SO₃),Se(Na₂SeO₃)and Te(Na₂TeO₃)in S family on the growth of Spirulina maximum and S.platensis were investigated.It was shown that Se and Te had toxicity to two species of Spirulina,and toxicity of Te was stronger than that of Se obviously.In a specific range of concentration,sulfur could detoxificate the toxicity of Se and Te to a certain degree,but in high concentration this function declined,and Se also could detoxificate the toxicity of Te.But at the higher concentration,toxicity of Se and Te cooperated with each other.S,Se and Te could bring different effect on these two species obviously.To S.maximum,as increasing of S(Ⅳ)concentration the detoxifcation function to high concentration of Se enhanced. When S(Ⅳ)concentration reached 600 mg·L^-1,it detoxifcated toxicity of 600 mg·L^-1Se(Ⅳ)completely.But detoxifcation function of S to Te was weak.At the anaphase of S.maximum growth,25 mg·L^-1Se could detoxifcate the toxicity of Te partly.To S. platensis,detoxifcation function of 50 mg·L^-1S(Ⅳ)to Se and 200 mg·L^-1S(Ⅳ)to Te was maximal,but it couldn't detoxifcate toxicity of 600 mg·L^-1Se 或 200 mg·L^-1Te completely.The detoxifcation function of 50 mg·L^-1Se to Te was maximal.But the toxicity of 200 mg·L^-1Se cooperated with Te.