The effects of nitrate and nitrite pollution in drinking water source on cancer mortality were explored. The data ofNitrate. Nitrite for the drinking water sources and cancer mortality for Guangzhou city from 1991 to 1998 were collected, andtheir correlations were analyzed. The results showed that there was a positivc co-relationahip between the total concentation of N-nitrate together with N-nitrite in drinking water source and cancer mortality (R2=0.76, P<0.05). Study on the districts ofGuangzhou city showed a high correlation between N-nitrite and cancer mortality(R2=0.56, P<0.05), and the correlationbetween N-nitrate and cancer mortality was also high(R2=0.66, P<0.01). It indicated that from 1991 to 1998, the increase incancer mortality with the years among residents of Guangzhou city was relatal to the increasing concentration of nitrate andnitrite in the drinking water sources. The results showed the possibility that the nitrate and nitrite in drinking water source wereimportant factors which could induce cancer.
邓熙, 林秋奇, 顾继光. 广州市饮用水源中硝酸盐亚硝酸盐含量与癌症死亡率联系[J]. , 2004, 23(1): 38-41.
DENG Xi, LIN Qiu-qi, GU Ji-Guang. Correlation between concentration of Nitrate、Nitrite in drinking water source and cancer mortality for Guangzhou City. , 2004, 23(1): 38-41.
[1] Mirvish S S.1995.Role of N-nitroso compounds (NOC) and N-nitrosation in etiology of gastric,esophageal,nasopharyngeal and bladder cancer and contribution to cancer of known exposures to NOC[J].Cancer Lett,93(1):17-48.
[8] Gulis G,Czompolyova M,Cerhan JR.2002,An ecologic study of nitrate in municipal drinking water and cancer incidence in Tmava district,Slovakia [J].Environ Res,88(3):182-187.
[9] Sandor J,Kiss I,Farkas O,et al.2001,Association between gastric cancer mortality and nitrate content of drinking water:Ecological study on small area inequalities [J].Eur J Epidemiol,17(5):443-447.