The acute toxicity and effects of PCB1254 upon zebrafish(Brachydanio rerio)and its tissue structures
NIE Xiang-ping1, ZHANG Feng-jun2, LAN Chong-yu3
1. Institute of Hydrobiology, Jinan University, Guangzhou 510632, China; 2. Department of biology, South China Normal University, Guangzhou 510631 China; 3. School of life Science, Zhongshan University, Guangzhou 510275, China
The sub-acute toxicity test was conducted for PCB1254 upon the zebrafish(Brachydanio rerio). Results showed that the no observed effect concentration of PCB1254 is 0.40μg·L-1 and lowest observed effects concentration of PCB1254 is 2.0μg·L-1. The 30 d LD50 of PCB1254 on the zebrafish is 5.09μg·L-1. The morphology of gill and liver tissues were examined by transmission electron microscope. The results showed that the epithelium cells of gill tissue collapsed and top cell of secondary lamella of gill swelled when zebrafish were exposed to PCB1254( >
2.μg·L-1)for 30 d. Some hepatic cells showed the atrophy and deformation accompanying a lot of lipofuscin granules deposition in cytoplasm under high concentration PCB1254(50μg·L-1).
聂湘平1, 张凤君2, 蓝崇钰3. 多氯联苯(PCB1254)对斑马鱼(Brachydanio rerio)毒性及其组织结构的影响[J]. , 2004, 23(2): 106-109.
NIE Xiang-ping1, ZHANG Feng-jun2, LAN Chong-yu3. The acute toxicity and effects of PCB1254 upon zebrafish(Brachydanio rerio)and its tissue structures. , 2004, 23(2): 106-109.
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